Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABO_0032Conserved hypothetical protein; Identified by sequence similarity. InterPro: Thioredoxin. (308 aa)    
Predicted Functional Partners:
dsbG
Thiol:disulfide interchange protein DsbG; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
 
 0.885
msrA-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.840
ABO_1933
(Sco1/SenC family protein) identifiedby sequence similarity; putative; Family membership.
 
 
 0.696
dsbD
Thiol:disulfide interchange protein DsbD; Identified by match to PFAM protein family HMMPF00085 InterPro: Cytochrome c biogenesis protein transmembrane region; High confidence in function and specificity.
  
 
 0.680
ABO_0030
Sensor histidine kinase identified by sequence similarity; putative InterPro: Histidine kinase C-terminal; High confidence in function and specificity.
 
     0.623
ygiX
Transcriptional regulatory protein qseb; Probable 2-component transcription regulator identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; High confidence in function and specificity.
  
    0.580
lpdG
(2-oxoglutarate dehydrogenase lipoamidedehydrogenase component) identified by sequence similarity; putative catalytic activity: dihydrolipoamide + nad(+) = lipoamide + nadh; High confidence in function and specificity.
  
 0.561
ABO_0708
Oxidoreductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.515
ABO_0723
Oxidoreductase; Peroxiredoxin, antioxidant, AhpC/Tsa family, oxidoreductase (acting on NADH or NADPH with a disulfide as acceptor) identified by match to PFAM protein family HMMPF00578 InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Family membership.
  
 0.515
ahpC
Alkyl hydroperoxide reductase, C subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 0.515
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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