Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
serAD-3-phosphoglycerate dehydrogenase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF02826 InterPro: D-isomer specific 2-hydroxyacid dehydrogenase; High confidence in function and specificity. (409 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
 
 0.989
gpm
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 0.905
ABO_0067
Oxidoreductase with NAD+ or NADP+ as acceptor; Oxidoreductase FAD-binding putative identified by match to TIGR protein family HMMTIGR01679 InterPro: FAD linked oxidase C-terminal; Function unclear.
 
   
 0.702
ABO_0066
Fumarylacetoacetate hydrolase family protein) identified by match to PFAM protein family HMMPF01557 InterPro: Fumarylacetoacetate (FAA) hydrolase family; Family membership.
     
 0.606
ABO_0069
Conserved hypothetical protein belongs to the family DUF394 (protein of unknown function) identified by sequence similarity; putative InterPro: TPR repeat.
       0.518
ABO_0070
Hypothetical protein predicted by Glimmer/Critica.
       0.518
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
  
 0.463
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
    
 0.454
ABO_0071
Conserved hypothetical protein.
       0.424
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
    0.423
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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