Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0074CBS domain protein; Identified by sequence similarity; putative; Family membership. (200 aa)    
Predicted Functional Partners:
ABO_0669
Hypothetical protein predicted by Glimmer/Critica.
 
     0.673
ABO_0674
Conserved hypothetical protein.
  
     0.654
ABO_0667
(BNR domain protein) identified by match to PFAM protein family HMMPF02012 InterPro: BNR repeat BNR repaets are short repeats that were found in glycosyl hydrolases as well as other extracellular proteins of unknown function; Function unclear.
  
     0.636
alkS
alkB1GHJ regulator; This protein activates the expression of AlkB1 in the presence of alkanes.
  
     0.627
guaA-2
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
     
 0.567
ABO_0073
Conserved hypothetical protein; Region start changed from 77784 to 77655 (-129 bases) regional start was changed to be in accordance with the results of the observations.
       0.560
ABO_0672
Oxidoreductase (acting on paired donors with incorporation of molecular oxygen with NADH or NADPH as one donor, and incorporation of one atom of oxygen) identified by match to PFAM protein family HMMPF00355 InterPro: Rieske iron-sulfur protein 2Fe-2S subunit; Family membership.
  
     0.559
ABO_0675
Transcriptional regulator, TetR family; Family membership.
 
     0.542
kefB
Glutathione-regulated potassium-protonantiporter; Identified by sequence similarity; putative InterPro: Na+/H+ exchanger; High confidence in function and specificity; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.532
ABO_0671
Oxidoreductase (acting on paired donors with incorporation of molecular oxygen with NADH or NADPH as one donor, and incorporation of one atom of oxygen) identified by match to PFAM protein family HMMPF00355 InterPro: Rieske iron-sulfur protein 2Fe-2S subunit; Family membership.
  
     0.512
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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