Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cheR(methyltransferase CheR-like) identified by match to PFAM protein family HMMPF00515; High confidence in function and specificity. (292 aa)    
Predicted Functional Partners:
ABO_0106
Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
 
 0.995
cheB-2
Protein-glutamate methylesterase; Identified by sequencesimilarity; putative InterPro: CheB methylesterase; High confidence in function and specificity.
  
 0.995
cheB
(protein-glutamate methylesterase CheB) identified by sequencesimilarity; putative InterPro: CheB methylesterase; High confidence in function and specificity.
 
  
 0.980
chpA
ChpA two-component hybrid sensor and regulator, putative identified by match to TIGR protein family HMMTIGR01387 InterPro: Histidine kinase C-terminal still frameshift probable component of chemotactic signal transduction system; Specificity unclear.
 
  
 0.967
pilI
Type IV pili signal transduction protein PilI; Identified by match to PFAM protein family HMMPF01584 InterPro: CheW-like domain; High confidence in function and specificity.
 
  
 0.902
ABO_1307
Sensor histidine kinase/respose regulator, contains HisKA, HATPase_c and two Response_reg receiver domains; identified by sequencesimilarity; putative InterPro: Histidine kinase C-terminal; Family membership.
 
  
 0.799
ABO_1853
(sensor histidine kinase/response regulator, putative) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; Family membership.
  
 0.786
ABO_2520
Sensor histidin kinase, contains PAS-fold, HisKA and HATPase_c domains; conserved hypothetical protein.
  
 0.763
cheW
(chemotaxis protein, putative), pfam01584, CheW, CheW-like domain; conserved hypothetical protein.
 
  
 0.753
ABO_2433
Conserved hypothetical protein, signal transduction protein containing a membrane domain, an EAL and a GGDEF domain and PAS/PAC domain.
  
 0.734
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.