tonB protein (Alcanivorax borkumensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

tonB

TonB; Periplasmic protein TonB, links inner and outer membranes; Family membership. (292 aa)

Predicted Functional Partners:

exbB1

0.905

exbD1

0.891

ABO_1104

0.803

ABO_2012

0.772

ABO_1464

0.743

tolQ

0.732

cheW

0.699

gshB

0.688

chpA

0.686

ABO_0106

0.680

Your Current Organism:

Alcanivorax borkumensis

NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABO_0106	ABO_1464	ABO_0106	ABO_1464	Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.	Conserved hypothetical protein; Identified by sequence similarity.	0.634
ABO_0106	ABO_2012	ABO_0106	ABO_2012	Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.	Conserved hypothetical protein.	0.587
ABO_0106	cheW	ABO_0106	ABO_0102	Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.	(chemotaxis protein, putative), pfam01584, CheW, CheW-like domain; conserved hypothetical protein.	0.975
ABO_0106	chpA	ABO_0106	ABO_0104	Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.	ChpA two-component hybrid sensor and regulator, putative identified by match to TIGR protein family HMMTIGR01387 InterPro: Histidine kinase C-terminal still frameshift probable component of chemotactic signal transduction system; Specificity unclear.	0.998
ABO_0106	gshB	ABO_0106	ABO_0110	Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.	Glutathione synthetase; Identified by match to TIGR protein family HMMTIGR01380 InterPro: Prokaryotic glutathione synthetase ATP-binding domain; High confidence in function and specificity; Belongs to the prokaryotic GSH synthase family.	0.407
ABO_0106	tonB	ABO_0106	ABO_0111	Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.	TonB; Periplasmic protein TonB, links inner and outer membranes; Family membership.	0.680
ABO_1104	exbD1	ABO_1104	ABO_1054	Outer membrane siderophore receptor putative identified by sequence similarity; putative InterPro: TonB-dependent receptor protein; Function unclear.	InterPro: Biopolymer transport protein ExbD/TolR; Specificity unclear.	0.404
ABO_1104	tonB	ABO_1104	ABO_0111	Outer membrane siderophore receptor putative identified by sequence similarity; putative InterPro: TonB-dependent receptor protein; Function unclear.	TonB; Periplasmic protein TonB, links inner and outer membranes; Family membership.	0.803
ABO_1464	ABO_0106	ABO_1464	ABO_0106	Conserved hypothetical protein; Identified by sequence similarity.	Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.	0.634
ABO_1464	ABO_2012	ABO_1464	ABO_2012	Conserved hypothetical protein; Identified by sequence similarity.	Conserved hypothetical protein.	0.753
ABO_1464	cheW	ABO_1464	ABO_0102	Conserved hypothetical protein; Identified by sequence similarity.	(chemotaxis protein, putative), pfam01584, CheW, CheW-like domain; conserved hypothetical protein.	0.656
ABO_1464	chpA	ABO_1464	ABO_0104	Conserved hypothetical protein; Identified by sequence similarity.	ChpA two-component hybrid sensor and regulator, putative identified by match to TIGR protein family HMMTIGR01387 InterPro: Histidine kinase C-terminal still frameshift probable component of chemotactic signal transduction system; Specificity unclear.	0.645
ABO_1464	exbB1	ABO_1464	ABO_1053	Conserved hypothetical protein; Identified by sequence similarity.	MotA/TolQ/ExbB proton channel family protein identified by match to PFAM protein family HMMPF01618; High confidence in function and specificity.	0.418
ABO_1464	tonB	ABO_1464	ABO_0111	Conserved hypothetical protein; Identified by sequence similarity.	TonB; Periplasmic protein TonB, links inner and outer membranes; Family membership.	0.743
ABO_2012	ABO_0106	ABO_2012	ABO_0106	Conserved hypothetical protein.	Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.	0.587
ABO_2012	ABO_1464	ABO_2012	ABO_1464	Conserved hypothetical protein.	Conserved hypothetical protein; Identified by sequence similarity.	0.753
ABO_2012	cheW	ABO_2012	ABO_0102	Conserved hypothetical protein.	(chemotaxis protein, putative), pfam01584, CheW, CheW-like domain; conserved hypothetical protein.	0.734
ABO_2012	chpA	ABO_2012	ABO_0104	Conserved hypothetical protein.	ChpA two-component hybrid sensor and regulator, putative identified by match to TIGR protein family HMMTIGR01387 InterPro: Histidine kinase C-terminal still frameshift probable component of chemotactic signal transduction system; Specificity unclear.	0.696
ABO_2012	tonB	ABO_2012	ABO_0111	Conserved hypothetical protein.	TonB; Periplasmic protein TonB, links inner and outer membranes; Family membership.	0.772
cheW	ABO_0106	ABO_0102	ABO_0106	(chemotaxis protein, putative), pfam01584, CheW, CheW-like domain; conserved hypothetical protein.	Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.	0.975