Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0118Transcriptional regulator LysR family identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; Family membership. (290 aa)    
Predicted Functional Partners:
ABO_2123
(transcriptional regulator, putative) identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family HTH reporting nucleic acid binding motif; Family membership.
  
     0.556
adhC
adhC; alcohol dehydrogenase class III, formaldehyde dehydrogenase hydroxyacid dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01751 InterPro: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
     
 0.549
ABO_2402
Transcriptional regulator, LysR family; Identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; Family membership; Belongs to the LysR transcriptional regulatory family.
  
   
 0.510
metR
Transcriptional activator MetR; (metR-1) identified by sequence similarity; putative InterPro: Bacterial regulatory protein LysR family; High confidence in function and specificity; Belongs to the LysR transcriptional regulatory family.
  
     0.453
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
 
 0.442
cysB
Transcriptional regulator for cysteine regulon; (transcriptional regulator CysB) identified by sequence similarity;putative InterPro: Bacterial regulatory protein LysR family; High confidence in function and specificity.
  
     0.429
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 
 0.414
ABO_0116
Esterase, putative; Serine hydrolase involved in the detoxification of formaldehyde.
       0.407
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: medium (42%) [HD]