Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
alkB2Alkane-1-monooxygenase; Catalyzes the hydroxylation of n-alkanes in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C8-C16 hydrocarbons; Belongs to the fatty acid desaturase type 1 family. AlkB subfamily. (382 aa)    
Predicted Functional Partners:
alkB1
Alkane 1-monooxygenase; Catalyzes the hydroxylation of n-alkanes and fatty acids in the presence of a NADH-rubredoxin reductase and rubredoxin. It preferably hydroxylases C5-C12 hydrocarbons. Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.
  
  
0.926
adhC
adhC; alcohol dehydrogenase class III, formaldehyde dehydrogenase hydroxyacid dehydrogenase family protein identified by match to TIGR protein family HMMTIGR01751 InterPro: Zinc-containing alcohol dehydrogenase superfamily; High confidence in function and specificity; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
    
 0.903
alkH
(aldehyde dehydrogenase family protein) identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; High confidence in function and specificity.
     
 0.901
aldh1
Identified by match to TIGR protein family HMMTIGR01722 InterPro: Aldehyde dehydrogenase family; Specificity unclear.
     
 0.900
ABO_1717
Flavodoxin reductases (ferredoxin-NADPH reductase)putative; (oxidoreductase FAD-binding putative) identified by sequencesimilarity; putative InterPro: Oxidoreductase FAD and NAD(P)-binding domain; Family membership.
 
  
 0.597
alkG
Rubredoxin; Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
 
  
 0.577
ABO_0121
Transcriptional regulator GntR family identified by match to PFAM protein family HMMPF00392 InterPro: Bacterial regulatory proteins GntR family; Specificity unclear.
       0.536
ABO_2136
Conserved hypothetical protein.
  
     0.528
rubA
Rubredoxin; Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
 
  
 0.492
ABO_1916
(conserved hypothetical protein) identified by sequencesimilarity; putative.
  
     0.492
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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