Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ech1(enoyl-CoA hydratase/isomerase family protein, putative) identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity. (284 aa)    
Predicted Functional Partners:
fadB2
Fatty oxidation complex; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
0.940
fadB-2
(fatty oxidation complex alpha subunit, enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase) identified by sequence similarity; putative InterPro: enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase; Family membership.
0.919
fadH
(2,4-dienoyl-CoA reductase FadH) identified by sequencesimilarity; putative InterPro: NADH:flavin oxidoreductase/NADH oxidase; High confidence in function and specificity.
 
  
 0.897
fadC
enoyl-CoA hydratase; Identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity.
 
    0.713
eno-2
(enoyl-CoA hydratase/isomerase family protein) identified by match to PFAM protein family HMMPF00378 InterPro: Enoyl-CoA hydratase/isomerase; High confidence in function and specificity.
 
  
0.683
fadA
(Acetyl CoA acetyltransferase) identified by sequence similarity; putative InterPro: Thiolase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.671
ABO_1772
InterPro: Acyl-CoA dehydrogenase pae:PA4435; Function unclear.
  
 0.659
acdA-3
acyl-CoA dehydrogenase; Identified by sequencesimilarity; putative; High confidence in function and specificity.
  
 0.646
acdA
acyl-CoA dehydrogenase; Identified by sequencesimilarity; putative InterPro: Acyl-CoA dehydrogenase; Family membership.
  
 0.635
ABO_0988
acyl-CoA dehydrogenase; Identified by sequencesimilarity; putative InterPro: Acyl-CoA dehydrogenase; Family membership.
  
 0.620
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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