Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
estB(lipase/esterase family protein) identified by sequence similarity; InterPro: Esterase/lipase/thioesterase/carboxylesterase family active site; High confidence in function and specificity. (319 aa)    
Predicted Functional Partners:
ABO_0194
Monooxygenase flavin-binding family (oxydoreductase with NADH or NADPH as one donor, and incorporation of one atom of oxygen) identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); conserved hypothetical protein.
 
    0.886
ABO_2107
(monooxygenase, putative) identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); High confidence in function and specificity.
    0.777
ABO_1097
Monooxygenase, flavin-binding family; Identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); Family membership.
    0.724
ABO_0288
Monooxygenase flavin-binding family identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); Function unclear.
 
    0.677
ABO_0196
Oxidoreductase short chaindehydrogenase/reductase family identified by match to TIGR protein family HMMTIGR01500 InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; conserved hypothetical protein.
       0.656
ABO_0197
Metal-dependent hydrolase, putative; Predicted metal-dependent hydrolase; conserved hypothetical protein.
       0.656
ABO_0282
Monooxygenase flavin-binding family identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); Family membership.
 
    0.646
estC
InterPro: Carboxylesterases type-B; High confidence in function and specificity.
 
   
 0.619
ABO_0190
Monooxygenase, putative; (monooxygenase flavin-binding family) identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); Family membership.
 
    0.609
ABO_2393
Monooxygenase, flavin-binding family; Identified by sequence similarity; putative InterPro: Flavin-containing monooxygenase (FMO); Family membership.
 
    0.586
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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