Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABO_0252Conserved hypothetical protein. (126 aa)    
Predicted Functional Partners:
cysG
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
 
 0.997
ABO_0251
Deacetylase family protein identified by sequence similarity; putative InterPro: Histone deacetylase family; Family membership.
       0.612
narH
narH. Respiratory nitrate reductase 1 beta chain; High confidence in function and specificity.
  
    0.464
fadA1
acetyl-CoA acyltransferase; Identified by sequence similarity; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Thiolase family.
       0.440
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
  
  
 0.426
ABO_0248
ABC export system membrane fusion protein identified by sequencesimilarity; putative InterPro: HlyD family secretion protein; Function unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.401
macB
ABC transporter, ATP-binding protein/permease, putative; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
       0.401
ABO_0250
Outer membrane protein identified by sequence similarity; putative InterPro: Outer membrane efflux protein; Function unclear.
       0.401
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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