Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gshA(glutamate-cysteine ligase) identified by sequence similarity; putative; High confidence in function and specificity; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (525 aa)    
Predicted Functional Partners:
gshB
Glutathione synthetase; Identified by match to TIGR protein family HMMTIGR01380 InterPro: Prokaryotic glutathione synthetase ATP-binding domain; High confidence in function and specificity; Belongs to the prokaryotic GSH synthase family.
  
 
 0.944
pepN
(aminopeptidase N, alpha-aminoacylpeptide hydrolase) identified by sequence similarity; putative InterPro: Aminopeptidase N APN (CD13); High confidence in function and specificity.
     
 0.921
ggt
Gamma-glutamyltransferase precursor; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF01019 InterPro: Gamma-glutamyltranspeptidase; High confidence in function and specificity.
    
 0.914
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
 0.909
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
cysK
(cysteine synthase A, O-acetylserine sulfhydrylase A, O- acetylserine (thiol)-lyase A, sulfate starvation-induced protein 5) identified by sequencesimilarity; putative InterPro: Pyridoxal-5-phosphate-dependent enzymes beta family; High confidence in function and specificity; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.822
glnA
(glutamine synthetase type I, glutamate-ammonia ligase) identified by sequence similarity; putative identified by match to TIGRFAM protein family HMMTIGR00653; High confidence in function and specificity.
     
 0.819
gdhA-2
(glutamate dehydrogenase, NAD(P)-specific glutamate dehydrogenase) identified by sequence similarity; putative identified by match to PFAM protein families HMMPF02812 and HMMPF00208 InterPro: Glutamate/leucine/phenylalanine/valine dehydrogenase; High confidence in function and specificity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.815
aspC
(aspartate aminotransferase, transaminase A) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00155 InterPro: Aminotransferases class-I; High confidence in function and specificity.
  
 
  0.800
ABO_1595
NAD-glutamate dehydrogenase; Region start changed from 1824508 to 1824409 (-99 bases).
     
  0.800
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.