Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pilH-2(PilH; regulatory protein pilH family) identified by sequence similarity; putative InterPro: Response regulator receiver domain; Family membership. (120 aa)    
Predicted Functional Partners:
ABO_0106
Methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.
 
 0.968
pilI
Type IV pili signal transduction protein PilI; Identified by match to PFAM protein family HMMPF01584 InterPro: CheW-like domain; High confidence in function and specificity.
 
 
 0.957
chpA
ChpA two-component hybrid sensor and regulator, putative identified by match to TIGR protein family HMMTIGR01387 InterPro: Histidine kinase C-terminal still frameshift probable component of chemotactic signal transduction system; Specificity unclear.
 
0.935
pilH
Identified by sequence similarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
  
  
 
0.903
gacS
Sensor/response regulator hybrid; (sensor histidine kinase/response regulator GacS) identified by sequence similarity; putative InterPro: Histidine kinase C-terminal; Family membership.
 
 
 0.876
pfeS
(sensor histidine kinase) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity.
 
 
 0.829
phoR-2
Sensory box histidine kinase PhoR; Identified by sequence similarity; putative InterPro: Histidine kinase C-terminal; Specificity unclear.
  
 
 0.829
ABO_0972
Phosphotransferase-histidinkinase, family protein; Phosphotransferases (with a nitrogenous group as acceptor) identified by match to PFAM protein family HMMPF04171 InterPro: Histidine kinase C-terminal; Family membership.
 
 
 0.816
ABO_2517
Two-component sensor protein; Identified by sequencesimilarity; putative InterPro: Histidine kinase C-terminal; Family membership.
 
 
 0.814
ABO_2520
Sensor histidin kinase, contains PAS-fold, HisKA and HATPase_c domains; conserved hypothetical protein.
 
 
 
 0.812
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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