STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0267Multidrug resistance protein; Putative secreted protein; Function unclear. (454 aa)    
Predicted Functional Partners:
ABO_0266
(cation multi-drug efflux pump, Transporter of the RND family of multidrug efflux pump, putative) identified by match to PFAM protein family HMMPF04165 InterPro: Acriflavin resistance protein; Family membership; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   
 0.954
tolC
(outer membrane efflux protein TolC) belongs to the prtf family of secretion proteins. Pfam: Outer membrane efflux protein, OEP; Family membership.
  
 0.880
ABO_0250
Outer membrane protein identified by sequence similarity; putative InterPro: Outer membrane efflux protein; Function unclear.
  
 
 0.796
ABO_0963
InterPro: Outer membrane efflux protein probably a component that vonfers multidrug resistance. could also be implicated in the secretion of the siderophore, pyoverdine. probably involved in the efflux of the siderophore across the outer membrane; Hypothetical protein.
  
 
 0.796
macB
ABC transporter, ATP-binding protein/permease, putative; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.781
mtdA
Multidrug resistance protein mdtA precursor; conserved hypothetical protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
0.638
ABO_2747
(RND efflux membrane fusion protein, putative); identify by sequence similarity, putative; Family membership; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
0.636
ABO_2523
(RND transporter membrane fusion protein) identified by match to TIGR protein family HMMTIGR01730 InterPro: HlyD family secretion protein; High confidence in function and specificity; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
0.602
ABO_0248
ABC export system membrane fusion protein identified by sequencesimilarity; putative InterPro: HlyD family secretion protein; Function unclear; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
    
 0.561
czcC1
Cobalt/zinc/cadmium efflux RND transporter outermembrane protein (CzcC family) identified by sequencesimilarity; putative InterPro: Outer membrane efflux protein; Family membership.
  
 
 0.560
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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