Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hslR(heat shock protein 15, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog)) identified by match to PFAM protein family HMMPF01479 InterPro: S4 domain; High confidence in function and specificity; Belongs to the HSP15 family. (128 aa)    
Predicted Functional Partners:
hslO
Chaperonin, 33 kDa; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
  
  
 0.953
ABO_0278
Identified by match to PFAM protein family HMMPF00702 InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership.
  
  
 0.905
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.862
rplQ
50S ribosomal protein L17; Identified by match to PFAM protein family HMMPF01196 InterPro: Ribosomal protein L17; High confidence in function and specificity.
   
 
 0.821
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
 
 0.793
rpmB
Ribosomal protein L28; Identified by sequencesimilarity; putative InterPro: Ribosomal protein L28; Function unclear; Belongs to the bacterial ribosomal protein bL28 family.
  
   0.791
rpmH
Ribosomal protein L34; Identified by match to PFAM protein family HMMPF00468 InterPro: Ribosomal protein L34; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bL34 family.
   
   0.786
rpmA
50S ribosomal protein L27; Identified by sequencesimilarity; putative InterPro: Ribosomal protein L27; High confidence in function and specificity; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.785
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.780
rpmG
Ribosomal protein L33; Identified by sequencesimilarity; putative InterPro: Ribosomal protein L33; Function unclear; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.774
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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