STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0278Identified by match to PFAM protein family HMMPF00702 InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership. (217 aa)    
Predicted Functional Partners:
gmk-2
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
  0.910
guaA-2
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
    
 0.906
hslR
(heat shock protein 15, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog)) identified by match to PFAM protein family HMMPF01479 InterPro: S4 domain; High confidence in function and specificity; Belongs to the HSP15 family.
  
  
 0.905
guaB
Inosine-5'-phosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.905
cpdB;
(cpdB) (2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor (5`-nucleotidase)) identified by sequence similarity; putative InterPro: 5-Nucleotidase; Family membership; Belongs to the 5'-nucleotidase family.
   
 
 0.904
ABO_1878
Conserved hypothetical protein distantly.
    
 0.902
purH
(phosphoribosylaminoimidazolecarboxamideformyltrans feras e/IMP cyclohydrolase) identified by sequence similarity; putative; High confidence in function and specificity.
    
  0.901
guaA
(glutamine amidotransferase class I) identified by match to TIGR protein family HMMTIGR00888; Family membership.
    
  0.900
ABO_0477
Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.900
hpt
Hypoxanthine phosphoribosyltransferase; Identified by sequence similarity; putative InterPro: Phosphoribosyl transferase; High confidence in function and specificity.
    
  0.900
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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