node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABO_2084 | cbpA | ABO_2084 | ABO_1662 | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | 0.906 |
ABO_2084 | cpn10; | ABO_2084 | ABO_0633 | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.828 |
ABO_2084 | cpn60; | ABO_2084 | ABO_0634 | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.862 |
ABO_2084 | dnaJ | ABO_2084 | ABO_0315 | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.911 |
ABO_2084 | grpE | ABO_2084 | ABO_0313 | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.958 |
ABO_2084 | hrcA | ABO_2084 | ABO_0312 | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.776 |
ABO_2084 | hslU | ABO_2084 | ABO_2245 | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | Heat shock protein HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.475 |
ABO_2084 | hslV | ABO_2084 | ABO_2244 | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | Heat shock protein HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.424 |
ABO_2084 | htpG | ABO_2084 | ABO_1489 | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | Heat shock protein HtpG; Molecular chaperone. Has ATPase activity. | 0.903 |
cbpA | ABO_2084 | ABO_1662 | ABO_2084 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | 0.906 |
cbpA | cpn10; | ABO_1662 | ABO_0633 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.604 |
cbpA | cpn60; | ABO_1662 | ABO_0634 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.794 |
cbpA | dnaK | ABO_1662 | ABO_0314 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.982 |
cbpA | grpE | ABO_1662 | ABO_0313 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.913 |
cbpA | hrcA | ABO_1662 | ABO_0312 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.683 |
cbpA | hslU | ABO_1662 | ABO_2245 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Heat shock protein HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.673 |
cbpA | hslV | ABO_1662 | ABO_2244 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Heat shock protein HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.468 |
cbpA | htpG | ABO_1662 | ABO_1489 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Heat shock protein HtpG; Molecular chaperone. Has ATPase activity. | 0.821 |
cpn10; | ABO_2084 | ABO_0633 | ABO_2084 | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | Conserved hypothetical protein identified by match to PFAM protein family HMMPF00012 InterPro: Heat shock protein hsp70. | 0.828 |
cpn10; | cbpA | ABO_0633 | ABO_1662 | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | 0.604 |