node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABO_1828 | ABO_1979 | ABO_1828 | ABO_1979 | Hypothetical protein. | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | 0.483 |
ABO_1828 | cbpA | ABO_1828 | ABO_1662 | Hypothetical protein. | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | 0.821 |
ABO_1828 | clpB | ABO_1828 | ABO_0479 | Hypothetical protein. | ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.483 |
ABO_1828 | cpn10; | ABO_1828 | ABO_0633 | Hypothetical protein. | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.721 |
ABO_1828 | cpn60; | ABO_1828 | ABO_0634 | Hypothetical protein. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.819 |
ABO_1828 | dnaJ | ABO_1828 | ABO_0315 | Hypothetical protein. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.821 |
ABO_1828 | dnaK | ABO_1828 | ABO_0314 | Hypothetical protein. | Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.898 |
ABO_1828 | grpE | ABO_1828 | ABO_0313 | Hypothetical protein. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.673 |
ABO_1979 | ABO_1828 | ABO_1979 | ABO_1828 | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | Hypothetical protein. | 0.483 |
ABO_1979 | cbpA | ABO_1979 | ABO_1662 | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | 0.619 |
ABO_1979 | cpn10; | ABO_1979 | ABO_0633 | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.516 |
ABO_1979 | cpn60; | ABO_1979 | ABO_0634 | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.507 |
ABO_1979 | dnaJ | ABO_1979 | ABO_0315 | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | Heat shock protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.613 |
ABO_1979 | dnaK | ABO_1979 | ABO_0314 | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | Heat shock protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.851 |
ABO_1979 | grpE | ABO_1979 | ABO_0313 | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.787 |
ABO_1979 | hrcA | ABO_1979 | ABO_0312 | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | Heat-inducible transcription repressor hrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.528 |
ABO_1979 | htpG | ABO_1979 | ABO_1489 | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | Heat shock protein HtpG; Molecular chaperone. Has ATPase activity. | 0.514 |
cbpA | ABO_1828 | ABO_1662 | ABO_1828 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | Hypothetical protein. | 0.821 |
cbpA | ABO_1979 | ABO_1662 | ABO_1979 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | (chaperone-associated ATPase, putative) identified by match to PFAM protein family HMMPF02861 InterPro: AAA ATPase superfamily; High confidence in function and specificity. | 0.619 |
cbpA | clpB | ABO_1662 | ABO_0479 | curved-DNA-binding protein DnaJ family identified by sequence similarity; putative InterPro: DnaJ C terminal domain; High confidence in function and specificity. | ATP-dependent Clp protease, ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.619 |