STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
mrcBPenicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (796 aa)    
Predicted Functional Partners:
ftsI
Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
 
 0.991
mrdA
Penicillin-binding protein 2, putative; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 0.979
ABO_2078
(penicillin-binding protein) identified by sequence similarity; putative InterPro: Penicillin binding protein transpeptidase domain penicillin-binding protein 1a (pbp-1a) (pbp1a) [includes: penicillin- insensitive transglycosylase (EC 2.4.2.-) (peptidoglycan tgase); penicillin-sensitive transpeptidase (EC 3.4.-.-) (dd-transpeptidase)]; High confidence in function and specificity.
 
 
0.938
mrcA
Penicillin-binding protein 1A (PBP-1a) (PBP1a),(Penicillin-insensitive transglycosylase),(Peptidoglycan TGase);(Penicillin-sensitive transpeptidase),(DD-transpeptidase)]. identified by sequence similarity; putative InterPro: Penicillin binding protein transpeptidase domain; High confidence in function and specificity.
 
 
0.938
dacA
D-alanyl-D-alanine-carboxypeptidase; (D-alanyl-D-alanine carboxypeptidase) identified by sequencesimilarity; putative InterPro: D-alanyl-D-alanine carboxypeptidase 1 (S11) family; High confidence in function and specificity; Belongs to the peptidase S11 family.
  
 
 0.935
mtgA
Peptidoglycantransglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
  
  
0.927
ABO_0900
(pbpC) (penicillin-binding protein 1C) identified by sequencesimilarity; putative InterPro: Penicillin binding protein transpeptidase domain; High confidence in function and specificity.
  
  
0.923
dacB
D-alanyl-D-alanine-carboxypeptidase; (D-alanyl-D-alanine carboxypeptidase) identified by match to PFAM protein family HMMPF02113 InterPro: D-Ala-D-Ala carboxypeptidase 3 (S13) family; High confidence in function and specificity.
     
 0.921
ABO_2243
Conserved hypothetical protein.
   
 
 0.889
mltG
Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
 
   
 0.841
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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