Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABO_0358Identified by match to PFAM protein family HMMPF00654 InterPro: Voltage gated chloride channels; Specificity unclear. (476 aa)    
Predicted Functional Partners:
ABO_0357
Conserved hypothetical protein.
  
    0.666
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
       0.601
ABO_0360
Conserved hypothetical protein.
       0.600
ABO_0361
Conserved hypothetical protein identified by sequencesimilarity; putative; Function unclear.
       0.595
yadR
HesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
       0.595
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.504
thiD
Adenine phosphoribosyltransferase; (phosphomethylpyrimidine kinase) identified by sequencesimilarity; putative; High confidence in function and specificity.
       0.503
hemL
(glutamate-1-semialdehyde-21-aminomutase) identified by sequencesimilarity; putative InterPro: Glutamate-1-semialdehyde-21-aminomutase; High confidence in function and specificity.
       0.480
dagA
(sodium/alanine symporter, amino acid carrier protein alst, Na(+)-linked D-alanine/glycine permease, sodium/proton-dependent alanine carrier protein) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF01235 and TIGRFAM protein family HMMTIGR00835; putative InterPro: Sodium:alanine symporter family; High confidence in function and specificity.
  
    0.463
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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