Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yadRHesB/YadR/YfhF family protein; Required for insertion of 4Fe-4S clusters for at least IspG. (150 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase; Identified by sequence similarity; putative identified by match to PFAM potein family HMMPF00266; putative InterPro: Aminotransferase class-V; High confidence in function and specificity.
 
 
 0.821
ABO_0361
Conserved hypothetical protein identified by sequencesimilarity; putative; Function unclear.
       0.811
ABO_0360
Conserved hypothetical protein.
  
    0.807
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
       0.802
nfuA
yhgI conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.730
ABO_1644
Conserved hypothetical protein; Family membership.
 
 
 0.661
ydhD
Glutaredoxin-related protein; conserved hypothetical protein; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 0.617
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
     
 0.614
sufD
Permease component of ABC-tranporter; High confidence in function and specificity; conserved hypothetical protein, putative ABC transporter permease component, possibly involved in Fe-S cluster assembly.
  
 
 0.606
sucA
(kgdA) (2-oxoglutarate dehydrogenase E1 component) identified by sequence similarity; putative InterPro: Dehydrogenase E1 component; High confidence in function and specificity.
  
  
 0.602
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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