STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fadD(long-chain fatty-acid-CoA ligase putative) identified by match to TIGR protein family HMMTIGR01734 InterPro: AMP-dependent synthetase and ligase; High confidence in function and specificity. (560 aa)    
Predicted Functional Partners:
ABO_1581
Conserved hypothetical protein; Identified by match to PFAM protein family HMMPF01734.
 
 
 0.845
birA
biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
  
 0.844
coaX
Transcriptional activator, putative; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
       0.838
lip
Lipase; Identified by sequencesimilarity; putative InterPro: Esterase/lipase/thioesterase family active site; High confidence in function and specificity.
   
 
 0.808
ABO_0370
Conserved hypothetical protein.
       0.723
fadB-2
(fatty oxidation complex alpha subunit, enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase) identified by sequence similarity; putative InterPro: enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase; Family membership.
  
 
 0.491
fadB2
Fatty oxidation complex; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 
 0.491
ABO_0637
Putative membrane protein; Hypothetical protein, TMHMM: reporting 6 transmembrane helices.
   
 0.466
ABO_2083
Conserved hypothetical protein that shows an Ankyrin-repeat InterPro: Ankyrin-repeat.
   
 0.466
ABO_1784
Non-ribosomal peptide synthase fragment, contains condensation, fatty-acid-CoA ligase and thioesterase domains. identified by sequence similarity; putative InterPro: AMP-dependent synthetase and ligase; Family membership.
     
 0.425
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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