STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0370Conserved hypothetical protein. (215 aa)    
Predicted Functional Partners:
ABO_2012
Conserved hypothetical protein.
  
     0.766
birA
biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
       0.765
ABO_1227
Conserved hypothetical protein.
  
     0.764
cheW
(chemotaxis protein, putative), pfam01584, CheW, CheW-like domain; conserved hypothetical protein.
  
     0.751
ABO_1229
Hypothetical protein predicted by Glimmer/Critica.
  
     0.744
coaX
Transcriptional activator, putative; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
       0.735
fadD
(long-chain fatty-acid-CoA ligase putative) identified by match to TIGR protein family HMMTIGR01734 InterPro: AMP-dependent synthetase and ligase; High confidence in function and specificity.
       0.723
ABO_2444
Conserved hypothetical protein.
  
     0.705
ABO_1010
Hypothetical protein; InterPro: Cyclic nucleotide-binding domain.
  
     0.696
chpA
ChpA two-component hybrid sensor and regulator, putative identified by match to TIGR protein family HMMTIGR01387 InterPro: Histidine kinase C-terminal still frameshift probable component of chemotactic signal transduction system; Specificity unclear.
  
     0.685
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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