Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
algDGDP-mannose 6-dehydrogenase; Identified by sequence similarity; putative InterPro: UDP-glucose/GDP-mannose dehydrogenase family; High confidence in function and specificity. (437 aa)    
Predicted Functional Partners:
alg8
Alginate biosynthesis protein Alg8; Function unclear.
 
 
 0.993
algA
(mannose-1-phosphateguanylyltransferase/mannose-6-p hosphate isomerase) identified by match to PFAM protein family HMMPF00483 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 
 0.977
alg44
Alginate biosynthesis protein Alg44; Function unclear.
    
  0.960
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.944
galU
UTP-glucose-1-phosphate uridylyltransferase; Identified by match to TIGR protein family HMMTIGR01099 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity.
 
 0.912
algJ
Alginate O-acetylation protein AlgJ; High confidence in function and specificity.
 
  
 0.827
glmU
Bifunctional glmU protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
    
 0.825
algE
(outer membrane protein AlgE); High confidence in function and specificity.
  
  
 0.747
algI
Alginate O-acetylation protein AlgI; High confidence in function and specificity; Belongs to the membrane-bound acyltransferase family.
 
  
 0.735
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.728
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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