STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
algA(mannose-1-phosphateguanylyltransferase/mannose-6-p hosphate isomerase) identified by match to PFAM protein family HMMPF00483 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity; Belongs to the mannose-6-phosphate isomerase type 2 family. (477 aa)    
Predicted Functional Partners:
algC
Phosphomannomutase; Identified by sequence similarity; putative InterPro: Phosphoglucomutase and phosphomannomutase family; High confidence in function and specificity.
 
 0.987
algD
GDP-mannose 6-dehydrogenase; Identified by sequence similarity; putative InterPro: UDP-glucose/GDP-mannose dehydrogenase family; High confidence in function and specificity.
 
 
 0.977
pgm
Phosphoglucomutase/phosphomannomutase; Identified by sequence similarity; putative InterPro: Phosphoglucomutase and phosphomannomutase family; High confidence in function and specificity.
 
 0.962
pgi
Glucose-6-phosphate isomerase; Identified by sequencesimilarity; putative InterPro: Phosphoglucose isomerase (PGI); High confidence in function and specificity.
  
 
 0.959
galU
UTP-glucose-1-phosphate uridylyltransferase; Identified by match to TIGR protein family HMMTIGR01099 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity.
    
 0.946
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.936
galE-2
(UDP-glucose-4-epimerase),(Galactowaldenase),. identified by match to TIGR protein family HMMTIGR01746 InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
 
 0.936
glmS
Glucosamine 6-phosphate synthase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.924
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
    
 0.923
ugd2
(UDP-glucose dehydrogenase putative) identified by match to PFAM protein family HMMPF00984 InterPro: UDP-glucose/GDP-mannose dehydrogenase family; Specificity unclear.
 
 
 0.920
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.