Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ABO_0428DNA-binding response regulator LuxR family identified by match to PFAM protein family HMMPF00072 InterPro: Bacterial regulatory protein LuxR family; Family membership. (216 aa)    
Predicted Functional Partners:
ABO_1307
Sensor histidine kinase/respose regulator, contains HisKA, HATPase_c and two Response_reg receiver domains; identified by sequencesimilarity; putative InterPro: Histidine kinase C-terminal; Family membership.
  
 
 0.833
gacS
Sensor/response regulator hybrid; (sensor histidine kinase/response regulator GacS) identified by sequence similarity; putative InterPro: Histidine kinase C-terminal; Family membership.
   
 
 0.805
ABO_2518
(transcription regulator, putative)identified by sequence similarity; putative InterPro: Response regulator receiver domain; Family membership.
  
     0.766
gacA
DNA-binding response regulator GacA; Identified by sequence similarity; putative InterPro: Response regulator receiver domain; Specificity unclear.
  
   
 0.734
ABO_2155
(two-component protein: Na-solute symporter/sensory box histidinekinase/response regulator putative) identified by match to PFAM protein family HMMPF02518 and HMMPF00072; putative InterPro: Sodium:solute symporter family TMHMM: reportin 12 transmembrane helices; Family membership.
   
 
 0.561
ABO_2433
Conserved hypothetical protein, signal transduction protein containing a membrane domain, an EAL and a GGDEF domain and PAS/PAC domain.
  
 
 0.533
uvrA
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.521
ABO_1986
Unknown EC_number 21.7.3.11; (two-component sensor histidine kinase protein, putative) identified by match to PFAM protein family HMMPF03596 InterPro: Permeases for cytosine/purines uracil thiamine allantoin; Family membership.
   
 
 0.480
ABO_0429
Major facilitator family transporter identified by match to PFAM protein family HMMPF03605 InterPro: General substrate transporters; Family membership.
     
 0.460
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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