Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ribFFAD pyrophosphorylase; (riboflavin biosynthesis protein RibF) identified by sequence similarity; putative InterPro: Riboflavin kinase / FAD synthetase; High confidence in function and specificity; Belongs to the ribF family. (325 aa)    
Predicted Functional Partners:
truB
Pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 0.955
ribE
(riboflavin synthase, alpha subunit) identified by sequence similarity; putative InterPro: Riboflavin synthase alpha chain family lumazine binding domain; High confidence in function and specificity.
    
 0.940
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
 
    0.936
murJ
Membrane protein, MviN family; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
    
 0.915
ABO_2335
(hydrolase, haloacid dehalogenase-like family, putative) identified by match to TIGR protein family HMMTIGR01668 InterPro: Haloacid dehalogenase/epoxide hydrolase family; Family membership.
  
 
 0.914
cmk
Cytidylate kinase; Identified by sequence similarity; putative InterPro: Cytidylate kinase; High confidence in function and specificity.
 
  
 0.884
lspA-2
Signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
  
 0.807
fkpB
Peptidyl-prolyl cis-trans isomerase FKBP-type identified by sequencesimilarity; putative InterPro: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase); Specificity unclear.
  
  
 0.759
ribD
(S)-2-hydroxy-fatty-acid dehydrogenase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 0.686
dhbP
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.605
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (20%) [HD]