Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilSTwo-component sensor histidine kinase; Identified by match to PFAM protein family HMMPF04306 InterPro: Histidine kinase C-terminal; High confidence in function and specificity. (544 aa)    
Predicted Functional Partners:
ABO_0471
Sigma-54 dependent DNA-binding response regulator.
 
 
 0.991
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
     
 0.909
pilG
Identified by sequencesimilarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
 
 0.814
pilH
Identified by sequence similarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
 
 0.813
pilH-2
(PilH; regulatory protein pilH family) identified by sequence similarity; putative InterPro: Response regulator receiver domain; Family membership.
 
 
 0.811
pilZ
Type IV pilus biogenesis protein, identified by sequence similarity to Pseudomonas syringae pv. tomato str. DC3000; High confidence in function and specificity.
  
  
 0.794
pilM
Type IV fimbrial biogenesis protein PilM.
  
   
 0.786
ABO_0473
Conserved hypothetical protein.
       0.780
chpA
ChpA two-component hybrid sensor and regulator, putative identified by match to TIGR protein family HMMTIGR01387 InterPro: Histidine kinase C-terminal still frameshift probable component of chemotactic signal transduction system; Specificity unclear.
 
   
 0.770
ABO_1464
Conserved hypothetical protein; Identified by sequence similarity.
  
  
 0.734
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.