close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0484Transcriptional regulator LysR family identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; Family membership. (295 aa)    
Predicted Functional Partners:
ABO_0146
Transcriptional regulator, LysR family; Identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.732
ABO_2427
Transcriptional regulator, LysR family; Identified by sequence similarity; putative InterPro: Bacterial regulatory protein LysR family; Family membership; Belongs to the LysR transcriptional regulatory family.
  
     0.658
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.600
ABO_0028
Transcriptional regulator LysR family identified by match to PFAM protein family HMMPF03466 InterPro: Bacterial regulatory protein LysR family; High confidence in function and specificity.
  
     0.462
ABO_1386
Conserved hypothetical protein TIGR00046; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
  
     0.424
gltB
Glutamate synthase, large subunit; Identified by sequencesimilarity; putative identified by match to PFAM protein family HMMPF04897 and HMMPF01645 InterPro: Ferredoxin-dependent glutamate synthase; High confidence in function and specificity.
  
  
 0.423
pssA
CDP-diacylglycerol-serine O-phosphatidyltransferase; Identified by match to PFAM protein family HMMPF03653; High confidence in function and specificity; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
    0.401
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.