Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (489 aa)    
Predicted Functional Partners:
pepN
(aminopeptidase N, alpha-aminoacylpeptide hydrolase) identified by sequence similarity; putative InterPro: Aminopeptidase N APN (CD13); High confidence in function and specificity.
  
 0.946
ggt
Gamma-glutamyltransferase precursor; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF01019 InterPro: Gamma-glutamyltranspeptidase; High confidence in function and specificity.
     
 0.932
gshB
Glutathione synthetase; Identified by match to TIGR protein family HMMTIGR01380 InterPro: Prokaryotic glutathione synthetase ATP-binding domain; High confidence in function and specificity; Belongs to the prokaryotic GSH synthase family.
   
 
 0.929
gshA
(glutamate-cysteine ligase) identified by sequence similarity; putative; High confidence in function and specificity; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.909
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.822
holC
DNA polymerase III, chi subunit; Identified by sequencesimilarity; putative; High confidence in function and specificity.
  
  
 0.814
aspC
(aspartate aminotransferase, transaminase A) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00155 InterPro: Aminotransferases class-I; High confidence in function and specificity.
   
  0.813
cysK
(cysteine synthase A, O-acetylserine sulfhydrylase A, O- acetylserine (thiol)-lyase A, sulfate starvation-induced protein 5) identified by sequencesimilarity; putative InterPro: Pyridoxal-5-phosphate-dependent enzymes beta family; High confidence in function and specificity; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  0.811
nagZ
Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
    
 0.698
gidB
Methyltransferase GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
      0.613
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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