STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. (195 aa)    
Predicted Functional Partners:
rfaE
LPS biosynthesis protein RfaE; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family.
  
 0.998
ABO_0007
Histidinol-phosphatase, putatitve; Identified by sequence similarity; putative identified by match to TIGRFAM protein family HMMTIGR00213; Function unclear.
  
 0.995
ABO_0583
Lipoprotein, putative; Protein which is posttranslationally modified by the attachment of at least one lipid or fatty acid, e.g. farnesyl, palmitate and myristate; Function unclear.
  
    0.887
ABO_2215
Heptosyltransferase II, putatative; Heptosyltransferase II; identified by sequence similarity; putative InterPro: Glycosyltransferase family 9 Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core; High confidence in function and specificity.
 
   
 0.794
ABO_0585
Conserved hypothetical protein; InterPro: Uncharacterised protein family UPF0102; Belongs to the UPF0102 family.
  
    0.758
ABO_0586
Lipoprotein, putative; Protein which is posttranslationally modified by the attachment of at least one lipid or fatty acid, e.g. farnesyl, palmitate and myristate; Function unclear.
 
    0.757
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
    
 
 0.739
waaF
(ADP-heptose--LPS heptosyltransferase II, putative); identify by similarity to InterPro IPR002201 and PFAM protein family PF01075. InterPro IPR002201; Glyco_trans_9. lipopolysaccharide core biosynthesis; High confidence in function and specificity.
 
   
 0.718
kpsF
KpsF/GutQ family protein identified by match to PFAM protein family HMMPF01380 InterPro: KpsF/GutQ family protein; Family membership.
     
 0.606
lpxC
UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
  
  
 0.575
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.