Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABO_06292-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (311 aa)    
Predicted Functional Partners:
ABO_0967
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
  0.970
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.936
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
  
 0.932
msrb
protein-methionine-S-oxide reductase; High confidence in function and specificity; Belongs to the MsrB Met sulfoxide reductase family.
 
      0.712
ABO_1334
Conserved hypothetical protein with some similarity to AlkB, DNA repair system specific for alkylated DNA.
   
    0.545
ampG
(muropeptide permease ampG, putative) identified by sequence similarity; putative identified by match to TIGRFAM protein family HMMTIGR00901; putative; Function unclear.
       0.543
ABO_0627
Conserved hypothetical protein; Identified by match to TIGR protein family HMMTIGR00636 InterPro: Protein of unknown function DUF80; Belongs to the Cob(I)alamin adenosyltransferase family.
       0.519
ABO_0628
InterPro: TonB-dependent receptor protein; Family membership.
       0.515
ABO_0631
Conserved hypothetical protein; Identified by match to TIGR protein family HMMTIGR00589 InterPro: Methylated-DNA--protein-cysteine methyltransferase.
       0.457
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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