Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABO_0636Conserved hypothetical protein; Identified by sequencesimilarity; putative InterPro: Rhomboid family shows homololgy to a Rhomboid-like protein. This family contains integral membrane proteins that arerelated to Drosophila rhomboid protein P20350. Members of this family are found in bacteria and eukaryotes. These proteins contain three strongly conserved histidines in the putative transmembrane regions that may be involved in the as yet unknown function of these proteins. (200 aa)    
Predicted Functional Partners:
ABO_0637
Putative membrane protein; Hypothetical protein, TMHMM: reporting 6 transmembrane helices.
 
 
 
 0.855
ABO_0997
Conserved hypothetical protein.
 
    0.738
ABO_0994
InterPro: Cyclic nucleotide-binding domain; Family membership.
 
  
 0.706
ABO_0432
Conserved hypothetical protein.
 
     0.681
ABO_2017
cAMP-dependent protein kinase regulatory chain; (cytochrome c551 peroxidase putative) identified by match to PFAM protein family HMMPF03150 InterPro: Cyclic nucleotide-binding domain; Family membership.
 
  
 0.643
gspL
General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
     0.618
ABO_2115
Hypothetical protein; Identified by sequence similarity.
 
     0.606
ABO_2005
Conserved hypothetical protein.
  
     0.579
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
       0.570
ABO_2003
Conserved hypothetical protein.
  
     0.552
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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