Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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ABO_0637Putative membrane protein; Hypothetical protein, TMHMM: reporting 6 transmembrane helices. (573 aa)    
Predicted Functional Partners:
ABO_0636
Conserved hypothetical protein; Identified by sequencesimilarity; putative InterPro: Rhomboid family shows homololgy to a Rhomboid-like protein. This family contains integral membrane proteins that arerelated to Drosophila rhomboid protein P20350. Members of this family are found in bacteria and eukaryotes. These proteins contain three strongly conserved histidines in the putative transmembrane regions that may be involved in the as yet unknown function of these proteins.
 
 
 
 0.855
ABO_0251
Deacetylase family protein identified by sequence similarity; putative InterPro: Histone deacetylase family; Family membership.
   
 0.673
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.671
ABO_2017
cAMP-dependent protein kinase regulatory chain; (cytochrome c551 peroxidase putative) identified by match to PFAM protein family HMMPF03150 InterPro: Cyclic nucleotide-binding domain; Family membership.
 
 
 0.669
ABO_1084
Serine (threonine) protein kinase; (pnk) identified by sequencesimilarity; putative InterPro: Serine/Threonine protein kinase; High confidence in function and specificity.
  
 0.659
ABO_1193
(SET domain protein lysine methyltransferase, putative) InterPro: SET-domain of transcriptional regulators (TRX EZ ASH1 etc); Family membership.
    
 0.615
ABO_2019
ATPase, AAA family; AAA-protein (ATPases associated with various cellular activities); Family membership.
    
 0.615
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
   
   0.592
hepA
RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
 0.569
ABO_1010
Hypothetical protein; InterPro: Cyclic nucleotide-binding domain.
  
 
 0.568
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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