STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (947 aa)    
Predicted Functional Partners:
prpC
Methylcitrate synthase putative identified by sequence similarity; putative InterPro: Citrate synthase; High confidence in function and specificity; Belongs to the citrate synthase family.
 
 0.986
icdA
(icd) (isocitrate dehydrogenase NADP-dependentprokaryotic-type) identified by match to TIGR protein family HMMTIGR00183 InterPro: Isocitrate dehydrogenase NADP-dependent prok type; High confidence in function and specificity.
 
 0.985
gltA
Citrate synthase; Identified by match to PFAM protein family HMMPF00285 InterPro: Citrate synthase; High confidence in function and specificity.
 
 0.985
ABO_1430
Conserved hypothetical protein; Identified by match to PFAM protein family HMMPF04303.
  
 
 0.971
icd
(isocitrate dehydrogenase NADP-dependent, oxalosuccinate decarboxylase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00180 and TIGRFAM protein family HMMTIGR00175 InterPro: Isocitrate and isopropylmalate dehydrogenases; High confidence in function and specificity.
  
 0.947
prpB
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 0.935
acnB
Aconitate hydratase 2; Identified by sequence similarity; putative InterPro: Aconitate hydratase 2; High confidence in function and specificity; Belongs to the aconitase/IPM isomerase family.
    
0.923
aceA
Isocitrate lyase; Identified by sequence similarity; putative InterPro: Isocitrate lyase first step in glyoxylate bypass, an alternative to the tricarboxylic acid cycle (in bacteria, plants, and fungi), belongs to the isocitrate lyase family; High confidence in function and specificity.
   
 
 0.921
icd-2
(isocitrate dehydrogenase NADP-dependent monomeric-type) identified by match to PFAM protein family HMMPF03971 InterPro: Isocitrate dehydrogenase NADP-dependent monomeric type; High confidence in function and specificity; Belongs to the monomeric-type IDH family.
 
 
 0.917
prpD
2-methylcitrate dehydratase; prpD) identified by sequencesimilarity; putative; Family membership.
  
 
 0.917
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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