Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rstB(sensor histidine kinase) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity. (541 aa)    
Predicted Functional Partners:
rstA
DNA-binding response regulator; Identified by sequence similarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
 0.993
phoB
Phosphate regulon transcriptional regulatory protein phoB; (DNA-binding response regulator PhoB) identified by sequence similarity; putative; High confidence in function and specificity.
 
 0.796
pfeR
DNA-binding response regulator; Identified by match to PFAM protein family HMMPF00072; Specificity unclear.
 
 
 0.783
ompR1
(ompR-1) identified by sequencesimilarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
 
 0.763
pilH-2
(PilH; regulatory protein pilH family) identified by sequence similarity; putative InterPro: Response regulator receiver domain; Family membership.
 
 
 0.754
pilH
Identified by sequence similarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
 
 0.752
phoP-2
DNA-binding heavy metal response regulator, putative; Identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Specificity unclear.
 
 
 0.747
colR
(DNA-binding heavy metal response regulator, putative) identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Specificity unclear.
 
 
 0.744
ABO_0625
Probable two-component response regulatory protein; Possible response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain. Identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Family membership.
 
 
 0.732
ABO_2001
(Transcriptional regulatory protein, putative) identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Family membership.
 
 
 0.726
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.