Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (497 aa)    
Predicted Functional Partners:
glpD
Glycerol-3-phosphate dehydrogenase; Identified by match to PFAM protein family HMMPF01266 InterPro: D-amino acid oxidase; High confidence in function and specificity.
 
 0.996
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.919
AKR1A1
(oxidoreductase aldo/keto reductase family) identified by match to TIGR protein family HMMTIGR01293 InterPro: Aldo/keto reductase family; Family membership.
   
 0.914
plsB
Glycerol-3-phosphate O-acyltransferase; Identified by match to TIGR protein family HMMTIGR00530 InterPro: Phospholipid and glycerol acyltransferase (from motifs_6.msf); High confidence in function and specificity; Belongs to the GPAT/DAPAT family.
     
 0.908
ABO_0426
Glycerophosphoryl diester phosphodiesterase precursor; Function unclear.
  
  
 0.883
ABO_2502
FAD-binding oxidoreductase.
  
 
 0.786
ABO_2578
Ham1 protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
      0.714
ABO_1042
Identified by match to PFAM protein family HMMPF03009 InterPro: Glycerophosphoryl diester phosphodiesterase; conserved hypothetical protein.
 
  
 0.704
ABO_2019
ATPase, AAA family; AAA-protein (ATPases associated with various cellular activities); Family membership.
   
  0.646
ABO_0815
Trypsin-like serine protease; Serine endopeptidase identified by sequence similarity; putative InterPro: Serine proteases trypsin family; Specificity unclear; Belongs to the peptidase S1C family.
   
 0.584
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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