Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0715GGDEF domain protein; Identified by match to PFAM protein family HMMPF00990; conserved hypothetical protein. (367 aa)    
Predicted Functional Partners:
luxR
DNA-binding response regulator, LuxR family; Identified by match to PFAM protein family HMMPF00072 InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
  
 0.905
pilH
Identified by sequence similarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
 
    0.885
ABO_0716
GGDEF domain protein identified by sequencesimilarity; putative; conserved hypothetical protein.
 
  
0.872
ABO_1309
Sensory box protein/response regulator; Identified by sequencesimilarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
 
 
  
 0.730
ABO_2433
Conserved hypothetical protein, signal transduction protein containing a membrane domain, an EAL and a GGDEF domain and PAS/PAC domain.
 
 
0.677
ABO_2443
Conserved hypothetical protein; Identified by sequencesimilarity.
 
 
0.597
ABO_2691
Sensory box protein; Identified by match to PFAM protein family HMMPF03466 InterPro: Domain of unknown function 2; Function unclear.
 
0.557
gacS
Sensor/response regulator hybrid; (sensor histidine kinase/response regulator GacS) identified by sequence similarity; putative InterPro: Histidine kinase C-terminal; Family membership.
 
  
 0.553
ABO_2132
Chemotaxis sensory transducer family protein; Identified by match to PFAM protein family HMMPF02743 InterPro: Metal dependent phosphohydrolase HD domain; Family membership.
  
  
 0.478
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
       0.445
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.