Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (302 aa)    
Predicted Functional Partners:
argG
Argininosuccinate synthase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00764 InterPro: Argininosuccinate synthase; High confidence in function and specificity; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 
 0.995
carA
(carbamoyl-phosphate synthase small subunit, carbamoyl-phosphate synthetase glutamine chain) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00988; putative InterPro: Glutamine amidotransferase class-I; High confidence in function and specificity; Belongs to the CarA family.
 
 
 0.994
carB
(carbamoyl-phosphate synthase large subunit, carbamoyl- phosphate synthetase ammonia chain) identified by sequence similarity; putative identified by match to PFAM protein families HMMPF02786 and HMMPF00289 InterPro: Carbamoyl-phosphate synthase; High confidence in function and specificity.
 
 
 0.994
argD
Acetylornithine aminotransferase; Identified by sequence similarity; putative InterPro: Aminotransferase class-III pyridoxal-phosphate; High confidence in function and specificity; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 0.994
argJ
Glutamate N-acetyltransferase/amino-acidacetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
 
 
 0.991
argH
Argininosuccinate lyase; Identified by sequence similarity; putative identified by match to TIGRFAM protein family HMMTIGR00838 InterPro: Delta crystallin; High confidence in function and specificity.
  
 0.980
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.946
argA
(amino-acid acetyltransferase, N-acetylglutamate synthase) identified by sequence similarity; putative InterPro: Aspartokinase superfamily; High confidence in function and specificity; Belongs to the acetyltransferase family. ArgA subfamily.
 
  
 0.940
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.926
pyrC
(dihydroorotase multifunctional complex type; DHOase) identified by sequencesimilarity; putative InterPro: Dihydroorotase multifunctional complex type; High confidence in function and specificity.
 
  
 0.913
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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