Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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gloA-2(lactoylglutathione lyase, methylglyoxalase, aldoketomutase, glyoxalase I, ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase) identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00903 InterPro: Glyoxalase I; High confidence in function and specificity. (127 aa)    
Predicted Functional Partners:
bla
Metallo-beta-lactamase family protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
 
 0.961
ABO_2386
Identified by match to PFAM protein family HMMPF00753 InterPro: Metallo-beta-lactamase superfamily; Family membership.
   
 0.923
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
  
 
0.913
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.815
ilvA
Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.810
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
ABO_0727
Conserved hypothetical protein.
       0.781
rimK
Ribosomal protein S6 modification protein; Identified by sequence similarity; putative InterPro: S6 modification enzyme RimK family protein; High confidence in function and specificity.
     
 0.778
ABO_0729
Deacylase, putative; (conserved hypothetical protein) identified by sequence similarity; putative.
       0.529
gor
Glutathione reductase; Identified by sequencesimilarity; putative InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity.
 
  
 0.471
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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