Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0771Conserved hypothetical protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (477 aa)    
Predicted Functional Partners:
arsC
Arsenate reductase; Identified by sequence similarity; putative; Family membership.
 
  
 0.709
perM
Permease PerM putative identified by sequence similarity; putative InterPro: Domain of unknown function DUF20; Specificity unclear.
     
 0.620
ABO_0772
Conserved hypothetical protein; Belongs to the sulfur carrier protein TusA family.
       0.565
ABO_0815
Trypsin-like serine protease; Serine endopeptidase identified by sequence similarity; putative InterPro: Serine proteases trypsin family; Specificity unclear; Belongs to the peptidase S1C family.
 
 
 0.542
ABO_2275
Conserved hypothetical protein.
 
 
   0.540
lptD
Conserved hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
  
 0.526
bamA
Outer membrane protein, bacterial surface antigen family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
   
 0.509
nlpD
Lipoprotein NlpD, putative; (lipoprotein NlpD) identified by sequence similarity; putative InterPro: Peptidase family M23/M37; Function unclear.
 
 
   0.479
surA
Survival protein surA precursor (Peptidyl-prolyl cis-trans isomerase surA); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
  
 0.464
dsbA
Thiol:disulfide interchange protein, DsbA family; Identified by sequencesimilarity; putative InterPro: DSBA oxidoreductase; High confidence in function and specificity.
 
   
 0.430
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.