Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0774AhpC/TSA family protein identified by match to PFAM protein family HMMPF00578 InterPro: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Family membership. (158 aa)    
Predicted Functional Partners:
ABO_0775
Glycine cleavage system transcriptional repressor, putative; Identified by sequence similarity; putative InterPro: ACT domain; Function unclear.
  
    0.758
dsbD-2
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.613
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
  
  
 0.560
glnE
Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
      0.474
ABO_0778
Metallo-beta-lactamase family protein; Identified by sequencesimilarity; putative InterPro: Metallo-beta-lactamase superfamily; Family membership.
       0.459
trxB
(thioredoxin reductase; NADP-thioredoxin reductase) identified by sequencesimilarity; putative InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity.
  
  
 0.449
trx-2
Thioredoxin; Identified by match to TIGR protein family HMMTIGR00411 InterPro: Thioredoxin; High confidence in function and specificity; Belongs to the thioredoxin family.
  
 
 0.444
purC
(phosphoribosylaminoimidazole-succinocarboxamidesyn thase) identified by sequence similarity; putative InterPro: SAICAR synthetase; High confidence in function and specificity.
       0.435
ABO_0777
Conserved hypothetical protein; (lipoprotein putative) identified by sequencesimilarity; putative.
  
    0.425
ahpF
(alkyl hydroperoxide reductase F subunit) identified by sequence similarity; putative InterPro: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; High confidence in function and specificity.
     
 0.418
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.