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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xerDIntegrase/recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (312 aa)    
Predicted Functional Partners:
dsbC
Protein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
 
  
 0.758
tnpA
(Transposon protein A, transposition regulatory protein tnpA homolog - Sphingomonas aromaticivorans plasmid pNL1, putative) InterPro: Phage integrase; High confidence in function and specificity; Belongs to the 'phage' integrase family.
  
     0.720
ftsK
Cell division protein FtsK; Identified by sequence similarity; putative InterPro: FtsK/SpoIIIE family This domain contains a putative ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli FTSK_ECOLI and the stage III sporulation protein E SpoIIIE; Family membership.
 
   
 0.706
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.604
ABO_0802
Conserved hypothetical protein; Identified by match to PFAM protein family HMMPF04226.
       0.593
topA
Type I DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA [...]
 
  
 0.488
hom
Homoserine dehydrogenase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00742 InterPro: Homoserine dehydrogenase; High confidence in function and specificity.
     
 0.475
ABO_0805
(aminotransferase, putative) identified by match to TIGR protein family HMMTIGR01141 and PFAM protein family HMMPF00155; putative InterPro: Aminotransferases class-I; Family membership.
       0.456
xerC
Integrase/recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
 
 
0.443
ABO_2221
Conserved hypothetical protein; (competence protein ComF putative) identified by sequence similarity; putative.
   
    0.432
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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