STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
dsbCProtein disulfide-isomerase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (247 aa)    
Predicted Functional Partners:
dsbD
Thiol:disulfide interchange protein DsbD; Identified by match to PFAM protein family HMMPF00085 InterPro: Cytochrome c biogenesis protein transmembrane region; High confidence in function and specificity.
  
 
 0.900
dsbA
Thiol:disulfide interchange protein, DsbA family; Identified by sequencesimilarity; putative InterPro: DSBA oxidoreductase; High confidence in function and specificity.
  
  
 0.810
xerD
Integrase/recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
 
  
 0.767
dsbB
Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
 
 
 0.756
lptD
Conserved hypothetical protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
  
 0.657
tatA
Sec-independent protein translocase protein tatA/E homolog; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
  
  
 0.585
ABO_0796
Membrane protein, putative; Identified by sequence similarity; putative; conserved hypothetical protein.
 
     0.560
omlA
Outer membrane lipoprotein OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.552
hom
Homoserine dehydrogenase; Identified by sequence similarity; putative identified by match to PFAM protein family HMMPF00742 InterPro: Homoserine dehydrogenase; High confidence in function and specificity.
       0.552
ABO_0805
(aminotransferase, putative) identified by match to TIGR protein family HMMTIGR01141 and PFAM protein family HMMPF00155; putative InterPro: Aminotransferases class-I; Family membership.
       0.550
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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