Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
colR(DNA-binding heavy metal response regulator, putative) identified by match to TIGR protein family HMMTIGR01387 InterPro: Response regulator receiver domain; Specificity unclear. (232 aa)    
Predicted Functional Partners:
colS
ColS protein; Identified by sequencesimilarity; putative; High confidence in function and specificity.
 
 
 0.853
pfeS
(sensor histidine kinase) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity.
 
 
 0.837
ABO_0030
Sensor histidine kinase identified by sequence similarity; putative InterPro: Histidine kinase C-terminal; High confidence in function and specificity.
 
 
 0.794
ABO_2000
Sensor histidine kinase; Identified by match to PFAM protein family HMMPF00512 InterPro: Histidine kinase C-terminal; Family membership.
 
 
 0.778
envZ
(ompB), (perA), (tpo). Osmolarity sensor protein EnvZ, protein histidine kinase/phosphatase sensor for OmpR, modulatesexpression of ompF and ompC) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity.
 
 
 0.776
phoR
Phosphate regulon sensor protein PhoR; (sensory box histidine kinase PhoR) identified by sequence similarity; putative InterPro: Histidine kinase C-terminal; High confidence in function and specificity.
 
 0.770
ABO_2155
(two-component protein: Na-solute symporter/sensory box histidinekinase/response regulator putative) identified by match to PFAM protein family HMMPF02518 and HMMPF00072; putative InterPro: Sodium:solute symporter family TMHMM: reportin 12 transmembrane helices; Family membership.
 
 
 0.768
rstB
(sensor histidine kinase) identified by match to PFAM protein family HMMPF02518 InterPro: Histidine kinase C-terminal; High confidence in function and specificity.
 
 
 0.744
pilH
Identified by sequence similarity; putative InterPro: Response regulator receiver domain; High confidence in function and specificity.
  
     0.724
ABO_0626
Phosphotransferase with a nitrogenous group as acceptor; Family membership.
 
 0.715
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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