Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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fabA3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (175 aa)    
Predicted Functional Partners:
fabB-2
(3-oxoacyl-(acyl-carrier-protein) synthase I) identified by match to PFAM protein family HMMPF02801 InterPro: Beta-ketoacyl synthase; High confidence in function and specificity; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.975
fabI
Enoyl-[Acyl-carrier-protein] reductase; Identified by sequence similarity; putative InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity.
  
 
 0.971
fabZ
(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
 
 0.967
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.917
ABO_0632
(oxidoreductase short chaindehydrogenase/reductase family) identified by sequencesimilarity; putative InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; Specificity unclear.
  
 
 0.907
fabG
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.907
fabG-2
3-oxoacyl-[acyl-carrier-protein] reductase; Identified by sequencesimilarity; putative InterPro: Short-chain dehydrogenase/reductase (SDR) superfamily; High confidence in function and specificity.
  
 
 0.907
fabD
Malonyl CoA-acyl carrier protein transacylase; Identified by sequencesimilarity; putative InterPro: Acyl transferase domain; High confidence in function and specificity.
  
  
 0.835
uahA
Urea carboxylase/allophanate hydrolase; Urea carboxylase; urease (ATP-hydrolysing); urea amidolyase/allophanate hydrolase [EC:6.3.4.6 3.5.1.54] identified by sequence similarity; putative InterPro: DUF183; Family membership.
  
  
 0.824
lpxA
acyl-[acyl-carrier-protein]--UDP-N-acetylglucosa mine O-acyl; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
  
 0.698
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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