Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABO_0884Nitroreductase family protein identified by match to PFAM protein family HMMPF00881 InterPro: Nitroreductase family; Family membership. (185 aa)    
Predicted Functional Partners:
ABO_0883
Conserved hypothetical protein.
  
    0.840
ABO_0882
Hypothetical protein.
  
    0.827
ABO_0885
Adenylate cyclase PA3217; Specificity unclear.
       0.594
ABO_0063
Conserved hypothetical protein.
  
  
 0.574
birA
biotin-[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.532
ABO_1848
(ABC transporter, ATP-binding protein/permease protein, putative) identified by match to PFAM protein family HMMPF03772 InterPro: AAA ATPase superfamily; Family membership.
  
  
 0.503
gltB
Glutamate synthase, large subunit; Identified by sequencesimilarity; putative identified by match to PFAM protein family HMMPF04897 and HMMPF01645 InterPro: Ferredoxin-dependent glutamate synthase; High confidence in function and specificity.
     
 0.464
ABO_2428
Identified by match to PFAM protein family HMMPF00903 InterPro: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; conserved hypothetical protein.
 
  
 0.439
acpD
Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family.
      
 0.417
ydaH
(Putative p-aminobenzoyl-glutamate transporter) identified by match to PFAM protein family ABG_transport; Family membership.
  
    0.412
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (32%) [HD]