STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
galE4-epimerase; Identified by match to TIGR protein family HMMTIGR01746; putative InterPro: Nucleoside-diphosphate dependent epimerase/dehydratase family; Specificity unclear. (346 aa)    
Predicted Functional Partners:
wbpO
(capsular polysaccharide biosynthesis protein/UDP-glucose dehydrogenase) identified by match to PFAM protein family HMMPF00984 InterPro: UDP-glucose/GDP-mannose dehydrogenase family The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcholol to an acid without the release of an aldehyde intermediate; Family membership.
 
 0.989
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.967
wbpM
Polysaccharide biosynthesis protein; Identified by sequence similarity; putative InterPro: Polysaccharide biosynthesis protein CapD type; Family membership.
  
 
 0.931
galE-2
(UDP-glucose-4-epimerase),(Galactowaldenase),. identified by match to TIGR protein family HMMTIGR01746 InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
 
0.929
glmU
Bifunctional glmU protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
  
 
 0.915
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
    
 0.904
rmlD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
  
 
 0.870
algA
(mannose-1-phosphateguanylyltransferase/mannose-6-p hosphate isomerase) identified by match to PFAM protein family HMMPF00483 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.868
galU
UTP-glucose-1-phosphate uridylyltransferase; Identified by match to TIGR protein family HMMTIGR01099 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity.
 
  
 0.866
lpxA
acyl-[acyl-carrier-protein]--UDP-N-acetylglucosa mine O-acyl; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
 0.842
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.