Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rmlBdTDP-glucose 4,6-dehydratase; Identified by match to TIGR protein family HMMTIGR01746 InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (360 aa)    
Predicted Functional Partners:
rmlD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
 
 0.999
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
 
 0.999
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
 
 0.999
wzx
Polysaccharide export protein, translocase; (imidazolonepropionase) identified by sequence similarity; putative InterPro: Polysaccharide biosynthesis protein; Specificity unclear.
  
  
 0.947
galE
4-epimerase; Identified by match to TIGR protein family HMMTIGR01746; putative InterPro: Nucleoside-diphosphate dependent epimerase/dehydratase family; Specificity unclear.
  
  
0.838
ABO_0912
(acetyltransferase, putative) identified by sequence similarity; putative; Family membership.
     
 0.787
ABO_0939
Cell surface polysaccharide transporter; InterPro: Polysaccharide biosynthesis protein Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon; Family membership.
  
  
 0.780
ABO_0916
Hypothetical protein.
       0.773
wbpO
(capsular polysaccharide biosynthesis protein/UDP-glucose dehydrogenase) identified by match to PFAM protein family HMMPF00984 InterPro: UDP-glucose/GDP-mannose dehydrogenase family The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcholol to an acid without the release of an aldehyde intermediate; Family membership.
 
  
 0.723
algD
GDP-mannose 6-dehydrogenase; Identified by sequence similarity; putative InterPro: UDP-glucose/GDP-mannose dehydrogenase family; High confidence in function and specificity.
  
  
 0.705
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.