Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wzxPolysaccharide export protein, translocase; (imidazolonepropionase) identified by sequence similarity; putative InterPro: Polysaccharide biosynthesis protein; Specificity unclear. (442 aa)    
Predicted Functional Partners:
rmlB
dTDP-glucose 4,6-dehydratase; Identified by match to TIGR protein family HMMTIGR01746 InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.947
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
  
 0.947
rmlC
dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
  
  
 0.947
rmlD
dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family.
  
  
 0.826
ABO_0912
(acetyltransferase, putative) identified by sequence similarity; putative; Family membership.
  
  
 0.797
galE
4-epimerase; Identified by match to TIGR protein family HMMTIGR01746; putative InterPro: Nucleoside-diphosphate dependent epimerase/dehydratase family; Specificity unclear.
  
  
 0.790
ABO_0916
Hypothetical protein.
       0.773
ABO_0925
Sugar transferase, putative; Identified by match to PFAM protein family HMMPF02397 This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways; Family membership.
 
  
 0.678
wzc
Putative tyrosine-protein kinase Wzc; Family membership; deleted EC_number 2.7.1.112.
  
  
 0.677
ABO_0924
(glycosyl transferase probable) group 1 family protein identified by sequence similarity; putative InterPro: Glycosyl transferases group 1; Family membership.
 
  
 0.630
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: medium (54%) [HD]