Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
galE-2(UDP-glucose-4-epimerase),(Galactowaldenase),. identified by match to TIGR protein family HMMTIGR01746 InterPro: NAD dependent epimerase/dehydratase family; High confidence in function and specificity; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (310 aa)    
Predicted Functional Partners:
galU
UTP-glucose-1-phosphate uridylyltransferase; Identified by match to TIGR protein family HMMTIGR01099 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity.
  
 0.972
ugd2
(UDP-glucose dehydrogenase putative) identified by match to PFAM protein family HMMPF00984 InterPro: UDP-glucose/GDP-mannose dehydrogenase family; Specificity unclear.
  
 
 0.943
algA
(mannose-1-phosphateguanylyltransferase/mannose-6-p hosphate isomerase) identified by match to PFAM protein family HMMPF00483 InterPro: ADP-glucose pyrophosphorylase; High confidence in function and specificity; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 
 0.936
ugd1
(GDP-mannose 6-dehydrogenase) identified by sequence similarity; putative InterPro: UDP-glucose/GDP-mannose dehydrogenase family; High confidence in function and specificity.
  
 
 0.936
galE
4-epimerase; Identified by match to TIGR protein family HMMTIGR01746; putative InterPro: Nucleoside-diphosphate dependent epimerase/dehydratase family; Specificity unclear.
 
 
0.929
rmlA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
    
 0.864
glmU
Bifunctional glmU protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
   
 0.858
ABO_0007
Histidinol-phosphatase, putatitve; Identified by sequence similarity; putative identified by match to TIGRFAM protein family HMMTIGR00213; Function unclear.
    
 0.848
ABO_0939
Cell surface polysaccharide transporter; InterPro: Polysaccharide biosynthesis protein Members of this family are integral membrane proteins. Many members of the family are implicated in production of polysaccharide. The family includes RfbX part of the O antigen biosynthesis operon; Family membership.
     
 0.611
pgi
Glucose-6-phosphate isomerase; Identified by sequencesimilarity; putative InterPro: Phosphoglucose isomerase (PGI); High confidence in function and specificity.
  
  
 0.575
Your Current Organism:
Alcanivorax borkumensis
NCBI taxonomy Id: 393595
Other names: A. borkumensis SK2, Alcanivorax borkumensis SK2, Alcanivorax borkumensis str. SK2, Alcanivorax borkumensis strain SK2
Server load: low (34%) [HD]